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Image Search Results
Journal: Frontiers in Behavioral Neuroscience
Article Title: Reconsolidation-Extinction Interactions in Fear Memory Attenuation: The Role of Inter-Trial Interval Variability
doi: 10.3389/fnbeh.2017.00002
Figure Lengend Snippet: Illustration of the experimental paradigm. (A) Subjects received fear conditioning on Day 1, which consisted of three CS-US pairings. On Day 2, subjects received either a retrieval CS or no retrieval CS, followed 1 h later by extinction (19 total CSs) with either fixed ITIs or variable ITIs. Average ITIs were 1 min in Experiment 1 and 2 min in Experiment 2 min. (B) In Experiment 2 min, the ITI variability was divided into three different categories: no variability (fixed), small variability and large variability. On Day 3, subjects received two unpaired USs (reinstatement). On Day 4, subjects received three unpaired CSs as a probe for reinstatement of fear. CS, conditional stimulus; US, unconditional stimulus; ITI, inter trial interval; ret, retrieval; min, minute.
Article Snippet: All behavioral procedures were conducted in standard
Techniques:
Journal: Frontiers in Behavioral Neuroscience
Article Title: Modulation of instrumental responding by a conditioned threat stimulus requires lateral and central amygdala
doi: 10.3389/fnbeh.2015.00293
Figure Lengend Snippet: Upper section: Experimental design for the modulatory task used in Experiment 2. The Pavlovian threat conditioning (PTC) session took place on the first day of training. Subjects underwent the suppression (cSup) and then facilitation (cFac) components. USAP refers to unsignaled approach training and unsignaled sidman active avoidance (USAA) to USAA training phases where the two-way shuttle response was acquired in reward vs. avoidance procedures. After recovery from CeA lesions, additional tests were conducted. Lower section: Data collected for Experiment 2. Suppression test data are presented in (A) in terms of responses per minute during the Pre CS and CS periods and (B) in terms of the suppression ratio ( CSresponding/CSresponding + PreCSresponding ). USAA training data are presented in (C) for each three-session block in terms of mean avoidance responses per block. Data from the pre-surgical tests for conditioned facilitation and conditioned suppression are presented on the left of (D) and the post surgical tests on the right side. These data are presented in terms of percent of Pre CS responding for each test. * p < 0.05.
Article Snippet: For Experiment 1, Context a was a
Techniques: Blocking Assay